Washington insiders say he will quit within six to eight months in frustration at their unwillingness to "bang heads together" to get policy pushed through.
Mr Emanuel, 50, enjoys a good working relationship with Mr Obama but they are understood to have reached an understanding that differences over style mean he will serve only half the full four-year term.
Friends say he is also worried about burnout and losing touch with his young family due to the pressure of one of most high profile jobs in US politics.
"I would bet he will go after the midterms," said a leading Democratic consultant in Washington. "Nobody thinks it's working but they can't get rid of him – that would look awful. He needs the right sort of job to go to but the consensus is he'll go."
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